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- Ibrutinib was originated by scientists at Celera Genomics as a tool compound in order to study BTK function.
- On November 13'th, 2013, Ibrutinib got the approval by the US FDA in order to treat the mantle cell lymphoma.
- On February 12th, 2014, the US FDA expanded the approval of use of ibrutinib in order to treat chronic lymphocytic leukemia (CLL).
- Later in the very next year (2015), ibrutinib 140 mg was approved in order to treat patients with Waldenström's macroglobulinemia.
- In the month of May, 2016, ibrutinib was approved in the US in order to treat patients with chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL).
- In the month of January, 2017, ibrutinib was approved in the US in order to treat adult patients with relapsed/refractory (R/R) marginal zone lymphoma (MZL) who needs systemic therapy and have taken minimum 1-prior anti-CD20-based therapy.
- In the month of August, 2017, ibrutinib was approved in order to treat graft-versus-host disease. It was the first medication approved by the Food and Drug Administration for this condition.
- In the month of February 2018, ibrutinib was approved in the tablet formulation for use in the United States.
- In the month of August, 2018, ibrutinib along with rituximab was approved in order to treat adult patients with Waldenström's macroglobulinemia (WM), a rare and incurable sort of NHL (non-Hodgkin's lymphoma).
- In the month of January, 2019, ibrutinib along with obinutuzumab was approved in order to treat adult patients with previously untreated chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL or SLL).
- In the month of April, 2020, the FDA expanded the use of ibrutinib to include its combination along with rituximab for the initial treatment of adult patients with small lymphocytic lymphoma (SLL) or chronic lymphocytic leukemia (CLL).
- The ibrutinib 140 mg price is around 1,122,192 INR for a supply of 90 capsules, depending on the pharmacy you visit and of course the brand you choose, because every brand have their own price. Any WHO-GDP & ISO certified pharmaceutical wholesaler company would be best in order to buy this medication.
