TAFFIC' is the generic version of Gilead's Biktarvy and has been authorized/approved by the Drug Controller General of India (DCGI). It is marketed and distributed by Hetero Healthcare in India. Taffic, a once-a-day single pill, is a combination of three drugs: Bictegravir (50 mg), Emtricitabine (200 mg), and Tenofovir Alafenamide (25 mg). This medicinal product is indicated to treat human immunodeficiency virus type (HIV-1) infection in those who have no antiretroviral treatment history or replacing the current antiretroviral regimen in those who have viral copies less than 50/mL in the blood at least for 90 days with no earlier treatment failure and resistance to any components.
This 3-in-1 fixed-dose combination (FDC) medication has showcased a promising antiviral efficacy as fixed-dose combination of bictegravir emtricitabine tenofovir alafenamide tends to develop a safety profile among HIV-infected individuals.
Taffic (Bictegravir 50 mg, Emtricitabine 200 mg, Tenofovir Alafenamide 25 mg) doesn’t destroy the HIV already incorporated in the body (in CD4 cells), instead, it is known for preventing HIV from creating multiple copies of itself. This slows the replication of HIV within the body and helps in order to minimize the risk of transmission of HIV to another individual. Your immune system is a defense system that can recover because of these tablets that help produce more CD4 cells to replace the cells that are virus-infected. These three combined antiretroviral medicines into a single tablet help take your dosage easily by resisting the intake of more pills in a single day.
Indication: The medicine taffic tablet is specifically used for adult patients as treatment of HIV- 1 infection and consist of the following three superior factors-
- Bictegravir (50mg)
- Emtricitabine (200 mg)
- Tenofovir Alafenamide (25 mg)
Administration and Dosage: Taffic (Bictegravir/Emtricitabine/Tenofovir Alafenamide) tablets are authorized for the position of HIV 1 virus in adult patients. A single tablet is taken daily with/without eating meals. Adults who are uninfected can take a single dose of 1-tablet by mouth in case of pre-liability prophylaxis. Continue taking this medicinal product for the prescribed time-span as advised by your health specialist. Patient's condition needs to be monitored throughout the therapy with biktarvy's generic (TAFFIC). Don’t discontinue this treatment in the middle, or else your probability/risk of HIV resistance may scale down. On missing a single dose of Bictegravir/Emtricitabine/Tenofovir Alafenamide tablets, you must take medication promptly when you remember unless it’s near a time to take the very next dose. In that scenario, skip the missed dose in order to avoid taking a double dose.
Side Effects: Like all other pharmaceutical medicinal products, tab taffic can be responsible for causing side effects. Let’s have a close look at the kind of side effects this medicine can have:
Common side effects:
- diarrhea
- depression
- headache
- dizziness
- feeling sick (nausea)
- abnormal dreams
- tiredness (fatigue)
Uncommon side effects:
- hives
- anemia
- vomiting
- itching
- rashes
- joint pain
- anxiety
- stomach pain
- sleep disorders
- suicidal behavior
- swelling of the lips, face, tongue or throat
- complications with digestion resulting in discomfort after meals
Warnings:
- Don’t give taffic tablets (Bictegravir, Emtricitabine, Tenofovir) to children and adults aged under 18 years.
- This medicine is not for pregnant or breast-feeding mothers. However, respective ones ask the health specialist for advice prior to taking this medication.
- If a woman has taken this medicine during the pregnancy then, a specialist may request regular blood tests and certain other diagnostic tests in order to monitor the development of the child.
- A few active substances that exist in this medicine may pass into the breast milk, therefore do not breast-feed during treatment to avoid passing the virus to the child. If a woman really wants to breastfeed then, she must talk to her health specialist first.
Precautions to be followed:
Taffic medicine must be consumed cautiously since a few hazardous adverse reactions may occur during the treatment. In case a patient don’t continue the antiretroviral therapy, then few reactions may occur-
- Hepatomegaly
- Steatosis renal toxicity
- Serious exacerbation of HBV
- Immune reconstitution syndrome lactic acidosis
National guidelines should be followed while you consider safety measures in order to inhibit the transmission.
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